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NEBIVALVE H Nebivolol (5mg) + HCTZ (12.5mg) NEBIVALVE H is used for treating hypertension (high blood pressure), offering the benefits of two different mechanisms of action to improve blood pressure control more effectively than either medication alone. This combination can be particularly useful for patients whose blood pressure is not adequately controlled with monotherapy. Nebivolol Nebivolol is a beta-blocker that works by reducing the heart rate and the force of heart muscle contraction. It is beta-1 selective, meaning it primarily affects the heart, with minimal effects on the bronchi and blood vessels. Additionally, it enhances nitric oxide release, leading to vasodilation, which helps lower blood pressure. Hydrochlorothiazide (HCTZ) HCTZ is a thiazide diuretic that works by decreasing the body's ability to retain water. It does this by increasing the amount of salt and water the kidneys remove from the blood, which helps to lower blood pressure. HCTZ also has a mild vasodilatory effect that contributes to its antihypertensive properties. NEBIVALVE H Benefits Enhanced Blood Pressure Control: The combination provides a synergistic effect that can lead to more significant blood pressure reductions than either component alone. The diuretic effect of HCTZ reduces plasma volume, and the vasodilatory effect of nebivolol lowers peripheral vascular resistance, both contributing to blood pressure lowering. Improved Compliance: Combining two medications into one pill can improve patient compliance by simplifying the treatment regimen. Reduced Side Effects: By using lower doses of each medication in combination, it's possible to reduce the potential for side effects associated with higher doses of monotherapy. For further information: EMAIL: info@sterispharma.com / contact@sterispharma.com CALL/WHATSAPP: 7877551268, 7849827488 BUY NOW https://www.sterisonline.com/product/nebivalve-h-133334