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NICOMALOM 1 Nicoumalone (1mg) NICOMALOM 1 is a pharmaceutical product containing Nicoumalone, a potent anticoagulant used primarily for the prevention and treatment of thromboembolic disorders. This article delves into the various aspects of Nicoumalone (1mg), including its uses, dosage, side effects, price, and an overall conclusion to provide a comprehensive understanding of this medication. Uses of Nicoumalone Nicoumalone, also known as Acenocoumarol, is an oral anticoagulant that works by inhibiting the synthesis of vitamin K-dependent clotting factors. These clotting factors are essential for blood coagulation, and their inhibition helps in preventing the formation of harmful blood clots. Nicoumalone is commonly prescribed for the following conditions: Deep Vein Thrombosis (DVT): Nicoumalone is used to prevent and treat DVT, a condition where blood clots form in the deep veins of the legs, which can lead to serious complications if not treated promptly. Pulmonary Embolism (PE): This medication is effective in preventing PE, a potentially life-threatening condition where blood clots travel to the lungs and block the pulmonary arteries. Atrial Fibrillation (AF): Patients with AF, a type of irregular heartbeat, are at an increased risk of stroke due to the formation of blood clots. Nicoumalone helps in reducing this risk. Prosthetic Heart Valves: Individuals with mechanical heart valves are prone to clot formation. Nicoumalone is used to prevent thromboembolism in such patients. Other Thromboembolic Disorders: It is also used in various other conditions where there is a high risk of clot formation, such as myocardial infarction and stroke. Dosage and Administration The dosage of Nicoumalone is individualized based on the patient’s condition, response to the medication, and the target International Normalized Ratio (INR), which is a measure of blood clotting. Typically, the treatment is initiated with a higher dose, followed by maintenance therapy. Here is a general guideline for dosage: Initial Dose: The initial dose may vary between 2-4 mg per day for the first 2-4 days, depending on the patient's INR response. Maintenance Dose: The maintenance dose usually ranges from 1-8 mg per day, adjusted to achieve the target INR, typically between 2.0 and 3.0 for most indications. Monitoring Regular monitoring of INR is crucial to ensure the effectiveness and safety of Nicoumalone therapy. Patients should undergo INR testing frequently, especially during the initiation phase and whenever there are changes in dose or other medications that might interact with Nicoumalone. Side Effects Like all medications, Nicoumalone can cause side effects, although not everyone will experience them. The most common side effects include: Bleeding: The primary risk of Nicoumalone therapy is bleeding, which can range from minor bruising to severe hemorrhage. Patients should report any unusual bleeding or bruising to their healthcare provider immediately. Allergic Reactions: Some individuals may experience allergic reactions, including rash, itching, and swelling. Gastrointestinal Disturbances: Nausea, vomiting, diarrhea, and abdominal pain can occur in some patients. Hair Loss: Although rare, some patients may experience hair thinning or loss. Liver Dysfunction: Elevated liver enzymes and jaundice have been reported in rare cases. Interactions Nicoumalone has significant interactions with various medications and dietary factors. It is essential for patients to inform their healthcare provider about all the medications they are taking, including over-the-counter drugs and supplements. Some notable interactions include: Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. This company, which is based in Navi Mumbai, holds certifications from WHO, GMP, and ISO. Its commitment is to provide high-quality drugs at affordable prices to its customers throughout India, following the rigorous guidelines set by the WHO. Steris offers the convenience of an online pharmacy where customers can easily buy medicines and enjoy the benefit of home delivery. At Steris, the mission is to supply a wide array of healthcare products designed to meet the varied needs of the medical community. Whether it is advanced treatments, medications for rare conditions, or basic health necessities, Sterispharma strives to serve the healthcare industry’s broad demands. The extensive product lineup from Steris includes treatments for various health areas such as Cardiology, Asthma, Respiratory issues, Nasal conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental care, and Dermatology. For further information: EMAIL: info@sterispharma.com / contact@sterispharma.com CALL/WHATSAPP: 7877551268, 7849827488 BUY NOW https://www.sterisonline.com
