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TELMISTRUM MT 25 Telmisartan (40mg), Metoprolol (25mg) TELMISTRUM MT is a therapeutic strategy employed in the management of hypertension (high blood pressure) and other cardiovascular conditions. TELMISTRUM MT leverages the complementary mechanisms of action of an angiotensin II receptor blocker (ARB) and a beta-blocker to achieve better control of blood pressure and provide cardiovascular protection. Here's an overview of each medication and the rationale for their combined use: Telmisartan Class: Angiotensin II Receptor Blocker (ARB) Mechanism: Telmisartan selectively blocks the binding of angiotensin II to its receptor (AT1) in vascular smooth muscle and the adrenal gland. This action inhibits the vasoconstrictive and aldosterone-secreting effects of angiotensin II, leading to vasodilation, reduced blood volume, and lower blood pressure. Benefits: It is particularly effective in protecting the kidneys and heart, making it a preferred choice for patients with hypertension and an increased risk of cardiovascular and renal diseases. Metoprolol Class: Beta-Blocker (specifically, a β1-selective or "cardioselective" beta-blocker) Mechanism: Metoprolol works by blocking beta-1 adrenergic receptors in the heart, reducing heart rate, cardiac output, and the release of renin from the kidneys. This leads to decreased blood pressure and reduced workload on the heart. Benefits: Metoprolol is often used in the treatment of hypertension, angina (chest pain), heart failure, and to improve survival after a heart attack. Its cardioselectivity makes it preferable for patients with respiratory conditions such as asthma, as it minimally affects beta-2 receptors in the lungs. TELMISTRUM MT Rationale: TELMISTRUM MT targets different aspects of the cardiovascular system: Telmisartan acts primarily on the vascular system to lower blood pressure, while Metoprolol reduces heart rate and myocardial oxygen demand. This complementary action can enhance blood pressure control and provide additional benefits in terms of cardiovascular risk reduction. Advantages: For patients with coexisting conditions such as coronary artery disease, heart failure, or a history of myocardial infarction, this combination not only offers effective blood pressure control but also heart rate management and reduced cardiac workload. Considerations: When using TELMISTRUM MT , it's essential to monitor for potential side effects, such as dizziness, fatigue, or hypotension, and adjust dosages as necessary. Patients with certain conditions, like severe asthma or chronic obstructive pulmonary disease (COPD), should use beta-blockers cautiously. For further information: Email: info@sterispharma.com / contact@sterispharma.com Call/WhatsApp: 7877551268, 7849827488 Buy Now: https://www.sterisonline.com/product/telmistrum-mt-25-133382
